Liquid Biopsy in Cancer Diagnosis and Treatment

Because of the vast improvements in the medical field, particularly in screening programs, early detection of various forms of cancer–including those that are asymptomatic–have become possible. This is important and beneficial in so many ways because it can drastically improve clinical outcomes, avoid improper treatment, etc. 

On top of the list is DNA next generation sequencing and here, liquid biopsy screening in Singapore is changing the playing field. Want to know more about it? Continue reading and find out why it is a great early cancer detection method. 

What makes liquid biopsy screening important? 

Liquid biopsy screening is based on the premise that the tumor materials that are shed in the body in the form of cell-free deoxyribonucleic acid (DNA). Many extensive studies suggest that demonstrated genomic testing that is complemented with advanced technology can detect genomic changes in the shed material that are obtained from bodily fluids. 

How does liquid biopsy screening work?

Before we talk about liquid biopsy, let’s take a look at conventional biopsy, one of the most common methods of cancer screening. Here, sample cells or tissues are extracted to determine the presence of cancer. While this is effective in pinpointing who is affected by the said ailment or otherwise, it is invasive and is associated with several complications that include infection, excessive bleeding, skin numbness, etc. 

Because of the vast improvements in the medical field, particularly in screening programs, early detection of various forms of cancer–including those that are asymptomatic–have become possible. This is important and beneficial in so many ways because it can drastically improve clinical outcomes, avoid improper treatment, etc. 

On top of the list is DNA next generation sequencing and here, liquid biopsy screening in Singapore is changing the playing field. Want to know more about it? Continue reading and find out why it is a great early cancer detection method. 

What makes liquid biopsy screening important? 

Liquid biopsy screening is based on the premise that the tumor materials that are shed in the body in the form of cell-free deoxyribonucleic acid (DNA). Many extensive studies suggest that demonstrated genomic testing that is complemented with advanced technology can detect genomic changes in the shed material that are obtained from bodily fluids. 

How does liquid biopsy screening work?

Before we talk about liquid biopsy, let’s take a look at conventional biopsy, one of the most common methods of cancer screening. Here, sample cells or tissues are extracted to determine the presence of cancer. While this is effective in pinpointing who is affected by the said ailment or otherwise, it is invasive and is associated with several complications that include infection, excessive bleeding, skin numbness, etc. 

This is not the case when it comes to liquid biopsy, a kind of DNA next generation sequencing that is used for cancer screening. Here, the biomolecules that tumors released in the bloodstream are collected. Afterward, they are separated from the plasma then analyze the following: 

  • Ribonucleic acid (RNA) and protein expression 
  • Deoxyribonucleic acid (DNA) and chromosomal abnormalities
  • Point mutations 
  • Deletions, amplifications, and translocations 

The aforementioned information are utilized to determine if cancer exists and find out which method of treatment is best, how a patient is responding to the treatment, and if the cancer returned. 

Summing up

Liquid biopsy is a relatively new kind of DNA next generation sequencing and it is restricted to certain forms of cancer: prostate cancer, breast cancer, colon cancer, and non-small cell lung cancer. Despite this, it is a milestone and has a very bright future when it comes to cancer treatment. 

For the time being, let us just enjoy the fact that early cancer detection can play a key role in improving the overall health and prolonging the lives of many. That being said, if you are interested in having one ask your healthcare professional about it. He or she can provide more extensive information about it and enable you to make a sound decision.

Because of the vast improvements in the medical field, particularly in screening programs, early detection of various forms of cancer–including those that are asymptomatic–have become possible. This is important and beneficial in so many ways because it can drastically improve clinical outcomes, avoid improper treatment, etc. 

On top of the list is DNA next generation sequencing and here, liquid biopsy screening in Singapore is changing the playing field. Want to know more about it? Continue reading and find out why it is a great early cancer detection method. 

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